Fatigue and pancreatic cancer

Fatigue is extreme tiredness, and it’s common for people with pancreatic cancer.

Key facts


  • Fatigue is extreme tiredness. It isn’t the same as just feeling tired. You might feel both mentally drained and physically exhausted.
  • It can impact your daily life, making it harder to do things like work and household tasks.
  • Fatigue isn’t always linked to how much activity you have been doing.
  • People often find fatigue hard to cope with as you may not be able to do things you have always done.

What is fatigue?

Fatigue is extreme tiredness and is a very common symptom of pancreatic cancer and cancer treatments.

People sometimes think that fatigue is something they have to put up with if they have cancer. It’s not always possible to relieve fatigue completely but there are things you and your medical team can do to help you manage it.

Doctor and patient consultation

What causes fatigue?

Fatigue can be caused by the cancer, symptoms of the cancer or treatments for the cancer. It's important to talk to your medical team about your fatigue so they can help to find the cause.

Read more

Watch our video about managing fatigue

Our specialist nurse, Jeni, explains how fatigue can affect people with pancreatic cancer and how it can be managed. Becki, Mark and Sharon share their experiences of fatigue.

Watch our video
Senior Patient Having Consultation With Doctor In Office

What can help with fatigue?

It’s not always possible to relieve fatigue completely. But there are other things you and your medical team can do to help you deal with it.

Read more

Dealing with the effects of fatigue

Fatigue can have a big impact on your daily life, and make it harder to do everything you used to do. But there are lots of practical ways to help manage cancer fatigue.

Read more
A woman in her 30s getting a cup of coffee for her father, a man in his 60s sitting at a table.

Supporting someone with fatigue

It can be upsetting when someone you love has fatigue, with no energy to do much. But there are lots of ways you can support them. And you may need support, too.

Read more

Read our booklet about fatigue

Download our booklet, Fatigue and pancreatic cancer, to read about fatigue.

Or you can order a printed copy of the booklet for free.

Order our Fatigue booklet

Speak to our nurses

You can speak to our specialist nurses on our confidential Support Line if fatigue is affecting you or someone you are caring for.

Speak to our nurses
Member of specialist nurse team

References and acknowledgements


References

We have listed some of the references to the sources used to write this information. If you would like the full list of references, email us at publications@pancreaticcancer.org.uk

  • Bootsma T.I., Schellekens M.P.J., van Woezik R.A.M., van der Lee M.L., Slatman J. Experiencing and responding to chronic cancer-related fatigue: A meta-ethnography of qualitative research. Psycho-Oncology [Internet].  01 Feb 2020 29(2):241-250
  • James S, Wright P, Scarlett C, Young T, Jamal H, Verma R. Cancer-related fatigue: results from patient experience surveys undertaken in a UK regional cancer centre. Support Care Cancer 2015;23:2089–2095. doi: 10.1007/s00520-014-2565-9
  • Mustian KM, Alfano CM, Heckler C, Kleckner AS, Kleckner IR, Leach CR et al. Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue A Meta-analysis. JAMA Oncol. 2017;3(7):961-968. doi:10.1001/jamaoncol.2016.6914
  • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). Cancer-related fatigue. Version 2.2022. [online] Available from: https://www.nccn.org/guidelines/guidelines-detail?category=3&id=1424

Acknowledgements

We would like to thank the following people who reviewed this information.

  • Monica Castro, Clinical Nurse Specialist, Western General Hospital, Edinburgh
  • Roopinder Gilmore, Consultant Medical Oncologist, Royal Free London NHS Foundation Trust
  • Jonathan Hartley, Accredited Counsellor, Supervisor, Trainer, Consultant, Rixon Therapy Services
  • Dr Joe Hutchinson, Academic GP, Loughborough University, Funded by the Wellcome Trust
  • Ollie Minton, Macmillan Consultant in Palliative Medicine, Brighton and Sussex University Hospitals NHS Trust
  • Pancreatic Cancer UK Lay Information Reviewers
  • Pancreatic Cancer UK Specialist Nurses

Published October 2025

To be reviewed October 2028

 

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