Advantages and disadvantages of clinical trials

If there is a trial that is suitable for you, think about the possible advantages and disadvantages and discuss these with your doctor or nurse. Have a look at our questions to ask your doctor or nurse. This will help you to decide if the trial is right for you.

Our video explains some of the main advantages and disadvantages of taking part in a clinical trial

Possible advantages

• You may have access to new treatments, which may only be available as part of a clinical trial.
• There may be fewer side effects compared to the standard treatment.
• You may have more regular tests, which some people find reassuring.
• You will be supported by a research nurse – who you can contact about your treatment and symptoms.
• You may help to improve future pancreatic cancer treatments and medical knowledge.

Possible disadvantages

• The new treatment may not be any better than your current treatment.
• There may be more side effects compared to the standard treatment.
• Trials may be carried out at a different hospital and involve travel, which can be tiring and take up a lot of time.
• You may have to go to hospital more often for tests and treatment, which can be inconvenient and tiring.
• You may not like not knowing whether you are taking a new drug, the standard treatment, or a placebo.

Find out as much as possible about the trial to help you to decide if you do want to take part. You can leave a clinical trial at any time, without it affecting your care.

Published February 2022

Review date February 2025